{"id":106100,"date":"2026-04-12T15:00:26","date_gmt":"2026-04-12T12:00:26","guid":{"rendered":"https:\/\/prizrenpost.com\/al\/konsumi-i-larte-i-mishit-mund-te-mbroje-nga-renia-njohese-tek-njerezit-me-nje-gjen-specifik-te-alzheimerit\/"},"modified":"2026-04-12T15:00:26","modified_gmt":"2026-04-12T12:00:26","slug":"konsumi-i-larte-i-mishit-mund-te-mbroje-nga-renia-njohese-tek-njerezit-me-nje-gjen-specifik-te-alzheimerit","status":"publish","type":"post","link":"https:\/\/prizrenpost.com\/al\/konsumi-i-larte-i-mishit-mund-te-mbroje-nga-renia-njohese-tek-njerezit-me-nje-gjen-specifik-te-alzheimerit\/","title":{"rendered":"Konsumi i lart\u00eb i mishit mund t\u00eb mbroj\u00eb nga r\u00ebnia njoh\u00ebse tek njer\u00ebzit me nj\u00eb gjen specifik t\u00eb Alzheimerit"},"content":{"rendered":"
\"Konsumi<\/figure>\n

T\u00eb moshuarit q\u00eb mbajn\u00eb nj\u00eb variacion specifik gjenetik t\u00eb lidhur me s\u00ebmundjen e Alzheimerit mund ta mbrojn\u00eb sh\u00ebndetin e trurit t\u00eb tyre duke ngr\u00ebn\u00eb nj\u00eb diet\u00eb t\u00eb pasur me mish.<\/p>\n

Nj\u00eb studim i koh\u00ebve t\u00eb fundit i botuar n\u00eb JAMA Network Open sugjeron q\u00eb rekomandimet e personalizuara dietike bazuar n\u00eb gjenetik\u00eb mund t\u00eb ndihmojn\u00eb n\u00eb parandalimin e r\u00ebnies njoh\u00ebse n\u00eb nj\u00eb pjes\u00eb t\u00eb madhe t\u00eb popullsis\u00eb globale.<\/p>\n

\u00c7do person mbart nj\u00eb gjen t\u00eb quajtur APOE, i cili jep udh\u00ebzime p\u00ebr prodhimin e nj\u00eb proteine q\u00eb ndihmon n\u00eb transportimin e yndyrnave dhe kolesterolit p\u00ebrmes qarkullimit t\u00eb gjakut. Ky gjen vjen n\u00eb tre versione kryesore, t\u00eb njohura si variante, t\u00eb quajtura e2, e3 dhe e4. Nj\u00eb person trash\u00ebgon nj\u00eb variant nga secili prind, duke krijuar kombinime t\u00eb ndryshme gjenetike. Apolipoproteinat jan\u00eb nj\u00eb familje proteinash q\u00eb lidhen me yndyrnat, duke luajtur nj\u00eb rol t\u00eb madh n\u00eb metabolizmin e kolesterolit n\u00eb m\u00ebl\u00e7i dhe tru.<\/p>\n

Varianti APOE e4 \u00ebsht\u00eb forma m\u00eb e vjet\u00ebr e gjenit n\u00eb historin\u00eb evolucionare t\u00eb njeriut. Ai u shfaq p\u00ebr her\u00eb t\u00eb par\u00eb miliona vjet m\u00eb par\u00eb, rreth koh\u00ebs kur paraardh\u00ebsit tan\u00eb t\u00eb hersh\u00ebm kaluan n\u00eb gjueti dhe filluan t\u00eb konsumonin sasi t\u00eb m\u00ebdha mishi. Disa antropolog\u00eb propozojn\u00eb q\u00eb paraardh\u00ebsit e njeriut kaluan n\u00ebp\u00ebr nj\u00eb periudh\u00eb disa milion vjet m\u00eb par\u00eb ku ata konsumonin dieta t\u00eb p\u00ebrb\u00ebra pothuajse t\u00ebr\u00ebsisht nga mishi. Kjo linj\u00eb kohore p\u00ebrputhet drejtp\u00ebrdrejt me shfaqjen e variantit APOE e4.<\/p>\n

Variantet m\u00eb t\u00eb reja, e3 dhe e2, u shfaq\u00ebn shum\u00eb m\u00eb von\u00eb n\u00eb historin\u00eb e njer\u00ebzimit. Popullatat njer\u00ebzore p\u00ebrfundimisht u zhvendos\u00ebn drejt bujq\u00ebsis\u00eb dhe filluan t\u00eb han\u00eb m\u00eb shum\u00eb ushqime me baz\u00eb bimore. Varianti e3 mendohet t\u00eb jet\u00eb shfaqur af\u00ebrsisht 200,000 vjet m\u00eb par\u00eb, duke reflektuar nj\u00eb p\u00ebrshtatje ndaj nj\u00eb diete omnivore. Sot, varianti e3 \u00ebsht\u00eb forma m\u00eb e zakonshme q\u00eb gjendet n\u00eb t\u00eb gjitha popullatat globale.<\/p>\n

N\u00eb koh\u00ebt moderne, varianti APOE e4 \u00ebsht\u00eb faktori m\u00eb i fort\u00eb i njohur i rrezikut gjenetik p\u00ebr s\u00ebmundjen Alzheimer me fillim t\u00eb von\u00eb. Njer\u00ebzit q\u00eb trash\u00ebgojn\u00eb kopje t\u00eb k\u00ebtij varianti kan\u00eb nj\u00eb shans shum\u00eb m\u00eb t\u00eb lart\u00eb p\u00ebr t\u00eb zhvilluar demenc\u00eb krahasuar me ata me kombinime t\u00eb tjera. N\u00eb Evrop\u00ebn Veriore dhe Amerik\u00ebn e Veriut, individ\u00ebt me kombinimet e3\/e4 ose e4\/e4 p\u00ebrb\u00ebjn\u00eb gati 70 p\u00ebrqind t\u00eb t\u00eb gjitha rasteve t\u00eb Alzheimerit.<\/p>\n

\n

Burimi: mesazhi<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00eb moshuarit q\u00eb mbajn\u00eb nj\u00eb variacion specifik gjenetik t\u00eb lidhur me s\u00ebmundjen e Alzheimerit mund ta mbrojn\u00eb sh\u00ebndetin e trurit t\u00eb tyre duke ngr\u00ebn\u00eb nj\u00eb diet\u00eb t\u00eb pasur me mish. Nj\u00eb studim i koh\u00ebve t\u00eb fundit i botuar n\u00eb JAMA Network Open sugjeron q\u00eb rekomandimet e personalizuara dietike bazuar n\u00eb gjenetik\u00eb mund t\u00eb ndihmojn\u00eb n\u00eb […]<\/p>\n","protected":false},"author":1,"featured_media":106099,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-106100","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-shendetesi"],"_links":{"self":[{"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/posts\/106100","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/comments?post=106100"}],"version-history":[{"count":0,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/posts\/106100\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/media\/106099"}],"wp:attachment":[{"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/media?parent=106100"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/categories?post=106100"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/tags?post=106100"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}