{"id":114768,"date":"2026-07-16T09:30:32","date_gmt":"2026-07-16T06:30:32","guid":{"rendered":"https:\/\/prizrenpost.com\/al\/pse-barnat-kunder-kolesterolit-shkaktojne-dhimbje-muskujsh-dhe-si-mund-te-parandalohet-kjo\/"},"modified":"2026-07-16T09:30:32","modified_gmt":"2026-07-16T06:30:32","slug":"pse-barnat-kunder-kolesterolit-shkaktojne-dhimbje-muskujsh-dhe-si-mund-te-parandalohet-kjo","status":"publish","type":"post","link":"https:\/\/prizrenpost.com\/al\/pse-barnat-kunder-kolesterolit-shkaktojne-dhimbje-muskujsh-dhe-si-mund-te-parandalohet-kjo\/","title":{"rendered":"Pse barnat kund\u00ebr kolesterolit shkaktojn\u00eb dhimbje muskujsh dhe si mund t\u00eb parandalohet kjo?"},"content":{"rendered":"
\"Pse<\/figure>\n

Zbulimi i ri tregon se problemi mund t\u00eb fshihet n\u00eb nj\u00eb mekaniz\u00ebm m\u00eb t\u00eb thell\u00eb, q\u00eb deri tani nuk ishte shpjeguar plot\u00ebsisht<\/p>\n

Miliona njer\u00ebz n\u00eb mbar\u00eb bot\u00ebn mb\u00ebshteten te statinat, nj\u00eb klas\u00eb barnash q\u00eb konsiderohen standard i art\u00eb p\u00ebr uljen e kolesterolit dhe zvog\u00eblimin e rrezikut nga sulmi n\u00eb zem\u00ebr dhe goditja n\u00eb tru.<\/p>\n

Megjithat\u00eb, te nj\u00eb num\u00ebr i konsideruesh\u00ebm pacient\u00ebsh, kjo terapi mund t\u00eb shkaktoj\u00eb probleme serioze: dhimbje muskujsh, dob\u00ebsi dhe intoleranc\u00eb t\u00eb theksuar ndaj aktivitetit fizik.<\/p>\n

Tani, studiuesit e McMaster University n\u00eb Kanada kan\u00eb identifikuar mekanizmin imunitar dhe metabolik q\u00eb nxit d\u00ebmtimin e indit muskulor, duke ndryshuar supozimet e deritanishme p\u00ebr efektet an\u00ebsore t\u00eb k\u00ebsaj terapie q\u00eb shp\u00ebton jet\u00eb.<\/p>\n

Problem q\u00eb prek deri n\u00eb 29 p\u00ebr qind t\u00eb pacient\u00ebve<\/p>\n

Studimi i ri i shkenc\u00ebtar\u00ebve nga McMaster University, i publikuar n\u00eb revist\u00ebn prestigjioze Science Advances, ka zbuluar rrug\u00ebn biologjike q\u00eb shpjegon pse shfaqen k\u00ebto efekte t\u00eb pad\u00ebshiruara.<\/p>\n

Ky zbulim hap mund\u00ebsin\u00eb p\u00ebr zhvillimin e terapive t\u00eb ardhshme q\u00eb do t\u00eb mund ta leht\u00ebsonin tolerimin e statinave, duke ruajtur plot\u00ebsisht p\u00ebrfitimet e tyre kardiovaskulare.<\/p>\n

Sipas vler\u00ebsimeve, simptomat muskulore t\u00eb shkaktuara nga statinat prekin nga 7 deri n\u00eb 29 p\u00ebr qind t\u00eb njer\u00ebzve q\u00eb i p\u00ebrdorin k\u00ebto barna.<\/p>\n

\u201cStatinat jan\u00eb nd\u00ebr barnat m\u00eb efikase q\u00eb kemi p\u00ebr uljen e rrezikut nga s\u00ebmundjet kardiovaskulare dhe parandalimin e vdekjes s\u00eb parakohshme. Fatkeq\u00ebsisht, efektet an\u00ebsore n\u00eb muskuj b\u00ebjn\u00eb q\u00eb shum\u00eb pacient\u00eb ta ulin doz\u00ebn me iniciativ\u00eb personale ose ta nd\u00ebrpresin plot\u00ebsisht trajtimin. Donim t\u00eb kuptonim pse ndodh kjo dhe n\u00ebse \u00ebsht\u00eb e mundur q\u00eb k\u00ebto efekte an\u00ebsore t\u00eb ndahen nga p\u00ebrfitimet q\u00eb kan\u00eb barnat kund\u00ebr kolesterolit\u201d, shpjegon autori kryesor i studimit, dr. Jonathan Schertzer, profesor n\u00eb Departamentin e Biokimis\u00eb dhe Shkencave Biomjek\u00ebsore n\u00eb McMaster University.<\/p>\n

Lidhja e papritur mes metabolizmit dhe imunitetit<\/p>\n

Ekipi hulumtues, i udh\u00ebhequr nga autor\u00ebt e studimit Nazli Robin dhe Nicole Barra nga Schertzer Lab n\u00eb McMaster University, zbuloi se statinat mund t\u00eb \u00e7rregullojn\u00eb m\u00ebnyr\u00ebn se si qelizat muskulore prodhojn\u00eb energji.<\/p>\n

Kjo, m\u00eb pas, nxit nj\u00eb p\u00ebrgjigje specifike imunitare brenda vet\u00eb qelizave. Pik\u00ebrisht ky reagim imunitar i lokalizuar dhe inflamacioni q\u00eb pason \u00e7ojn\u00eb n\u00eb d\u00ebmtimin e indit muskulor.<\/p>\n

N\u00eb eksperimentet me minj laboratorik\u00eb dhe me qeliza muskulore njer\u00ebzore, shkenc\u00ebtar\u00ebt arrit\u00ebn t\u00eb parandalonin pjes\u00ebn m\u00eb t\u00eb madhe t\u00eb d\u00ebmtimit t\u00eb muskujve duke bllokuar me sukses k\u00ebt\u00eb p\u00ebrgjigje imunitare.<\/p>\n

P\u00ebrfitimi i barnave kund\u00ebr kolesterolit mund t\u00eb ndahet nga efektet an\u00ebsore<\/p>\n

Gjetja m\u00eb interesante e k\u00ebtij hulumtimi \u00ebsht\u00eb se mekanizmi q\u00eb shkakton dhimbjen e muskujve \u00ebsht\u00eb plot\u00ebsisht i pavarur nga mekanizmi p\u00ebrmes t\u00eb cilit statinat ulin kolesterolin n\u00eb m\u00ebl\u00e7i.<\/p>\n

Kjo do t\u00eb thot\u00eb se mekanizmi i veprimit t\u00eb barnave dhe mekanizmi i efekteve an\u00ebsore jan\u00eb t\u00eb ndar\u00eb. Kjo hap mund\u00ebsin\u00eb q\u00eb industria farmaceutike, n\u00eb t\u00eb ardhmen, t\u00eb zhvilloj\u00eb barna t\u00eb synuara ose suplemente q\u00eb do t\u00eb bllokonin inflamacionin n\u00eb muskuj, nd\u00ebrsa statinat do t\u00eb vazhdonin pa penges\u00eb t\u00eb mbronin en\u00ebt e gjakut dhe zemr\u00ebn e pacientit.<\/p>\n

Edhe pse nevojiten studime klinike shtes\u00eb para se k\u00ebto rezultate laboratorike t\u00eb shnd\u00ebrrohen n\u00eb protokolle zyrtare p\u00ebr pacient\u00ebt, studimi ka hart\u00ebzuar me sakt\u00ebsi disa objektiva t\u00eb mundsh\u00ebm biologjik\u00eb p\u00ebr zhvillimin e barnave t\u00eb reja dhe p\u00ebr zgjidhjen e problemit t\u00eb intoleranc\u00ebs ndaj statinave.<\/p>\n

\n

Burimi: mesazhi<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Zbulimi i ri tregon se problemi mund t\u00eb fshihet n\u00eb nj\u00eb mekaniz\u00ebm m\u00eb t\u00eb thell\u00eb, q\u00eb deri tani nuk ishte shpjeguar plot\u00ebsisht Miliona njer\u00ebz n\u00eb mbar\u00eb bot\u00ebn mb\u00ebshteten te statinat, nj\u00eb klas\u00eb barnash q\u00eb konsiderohen standard i art\u00eb p\u00ebr uljen e kolesterolit dhe zvog\u00eblimin e rrezikut nga sulmi n\u00eb zem\u00ebr dhe goditja n\u00eb tru. Megjithat\u00eb, […]<\/p>\n","protected":false},"author":1,"featured_media":114767,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-114768","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-shendetesi"],"_links":{"self":[{"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/posts\/114768","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/comments?post=114768"}],"version-history":[{"count":0,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/posts\/114768\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/media\/114767"}],"wp:attachment":[{"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/media?parent=114768"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/categories?post=114768"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/tags?post=114768"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}