{"id":119314,"date":"2026-10-27T16:05:35","date_gmt":"2026-10-27T13:05:35","guid":{"rendered":"https:\/\/prizrenpost.com\/al\/vaksina-kunder-melanomes-jep-rezultate-te-jashtezakonshme-ul-me-42-rrezikun-e-rikthimit-te-kancerit-ose-vdekjes\/"},"modified":"2026-10-27T16:05:35","modified_gmt":"2026-10-27T13:05:35","slug":"vaksina-kunder-melanomes-jep-rezultate-te-jashtezakonshme-ul-me-42-rrezikun-e-rikthimit-te-kancerit-ose-vdekjes","status":"publish","type":"post","link":"https:\/\/prizrenpost.com\/al\/vaksina-kunder-melanomes-jep-rezultate-te-jashtezakonshme-ul-me-42-rrezikun-e-rikthimit-te-kancerit-ose-vdekjes\/","title":{"rendered":"Vaksina kund\u00ebr melanom\u00ebs jep rezultate t\u00eb jasht\u00ebzakonshme: Ul me 42% rrezikun e rikthimit t\u00eb kancerit ose vdekjes"},"content":{"rendered":"<figure class=\"post-featured-image\"><img decoding=\"async\" src=\"https:\/\/prizrenpost.com\/al\/wp-content\/uploads\/2026\/10\/14-7.jpg\" alt=\"Vaksina kund\u00ebr melanom\u00ebs jep rezultate t\u00eb jasht\u00ebzakonshme: Ul me 42% rrezikun e rikthimit t\u00eb kancerit ose vdekjes\"\/><\/figure>\n<p>Vaksina e personalizuar, e zhvilluar nga Moderna dhe Merck, ka dh\u00ebn\u00eb rezultate premtuese n\u00eb faz\u00ebn e tret\u00eb t\u00eb studimeve klinike. Trajtimi ka ulur edhe rrezikun e p\u00ebrhapjes s\u00eb kancerit n\u00eb organe t\u00eb tjera, duke hapur mund\u00ebsi t\u00eb reja p\u00ebr pacient\u00ebt me melanom\u00eb<\/p>\n<p>Nj\u00eb vaksin\u00eb e re kund\u00ebr melanom\u00ebs, form\u00ebs m\u00eb vdekjeprur\u00ebse t\u00eb kancerit t\u00eb l\u00ebkur\u00ebs, ka dh\u00ebn\u00eb rezultate shum\u00eb premtuese, duke ulur me 42 p\u00ebr qind rrezikun e rikthimit t\u00eb s\u00ebmundjes ose vdekjes, krahasuar me trajtimin standard.<\/p>\n<p>B\u00ebhet fjal\u00eb p\u00ebr intismeran autogene, nj\u00eb vaksin\u00eb terapeutike e personalizuar, e zhvilluar nga kompanit\u00eb farmaceutike Moderna dhe Merck, e cila p\u00ebrdor teknologjin\u00eb e ARN-s\u00eb mesazhere (mRNA) p\u00ebr t\u00eb ndihmuar sistemin imunitar t\u00eb njoh\u00eb dhe luftoj\u00eb qelizat kancerogjene.<\/p>\n<p>Sipas rezultateve t\u00eb publikuara m\u00eb 22 tetor 2026 nga Moderna dhe Merck, kombinimi i vaksin\u00ebs me imunoterapin\u00eb pembrolizumab (Keytruda) uli ndjesh\u00ebm mund\u00ebsin\u00eb e rikthimit t\u00eb melanom\u00ebs te pacient\u00ebt q\u00eb m\u00eb par\u00eb i ishin n\u00ebnshtruar operacionit p\u00ebr heqjen e tumorit.<\/p>\n<p>Rezultatet konsiderohen ve\u00e7an\u00ebrisht t\u00eb r\u00ebnd\u00ebsishme, pasi melanoma mund t\u00eb rikthehet edhe pas nd\u00ebrhyrjes kirurgjikale, nd\u00ebrsa n\u00eb fazat e avancuara mund t\u00eb p\u00ebrhapet n\u00eb organe t\u00eb tjera.<\/p>\n<p>Rreziku i p\u00ebrhapjes s\u00eb melanom\u00ebs u ul me 38 p\u00ebr qind<\/p>\n<p>Studimi klinik i faz\u00ebs s\u00eb tret\u00eb, i quajtur INTerpath-001, p\u00ebrfshiu 1.137 pacient\u00eb me melanom\u00eb t\u00eb stadit IIB deri n\u00eb IV, t\u00eb cil\u00ebve tumori u ishte hequr plot\u00ebsisht p\u00ebrmes operacionit.<\/p>\n<p>Nj\u00eb grup pacient\u00ebsh mori vaksin\u00ebn e personalizuar s\u00eb bashku me imunoterapin\u00eb Keytruda, nd\u00ebrsa grupi tjet\u00ebr mori Keytruda dhe placebo.<\/p>\n<p>Rezultatet treguan se kombinimi i vaksin\u00ebs me imunoterapin\u00eb uli me 42 p\u00ebr qind rrezikun relativ t\u00eb rikthimit t\u00eb melanom\u00ebs ose vdekjes. Nd\u00ebrkoh\u00eb, rreziku i shfaqjes s\u00eb metastazave n\u00eb pjes\u00eb t\u00eb larg\u00ebta t\u00eb trupit ose vdekjes u ul me 38 p\u00ebr qind.<\/p>\n<p>Sipas t\u00eb dh\u00ebnave t\u00eb raportuara nga Associated Press, pas dy vjet\u00ebsh, rreth 82 p\u00ebr qind e pacient\u00ebve q\u00eb kishin marr\u00eb vaksin\u00ebn dhe imunoterapin\u00eb ishin ende pa rikthim t\u00eb s\u00ebmundjes, krahasuar me 70 p\u00ebr qind t\u00eb atyre q\u00eb kishin marr\u00eb trajtimin standard.<\/p>\n<p>Megjithat\u00eb, t\u00eb dh\u00ebnat p\u00ebr mbijetes\u00ebn e p\u00ebrgjithshme nuk jan\u00eb ende p\u00ebrfundimtare. Kjo do t\u00eb thot\u00eb se mbetet p\u00ebr t\u2019u p\u00ebrcaktuar n\u00ebse trajtimi i ri do t\u00eb ndikoj\u00eb edhe n\u00eb zgjatjen e jet\u00ebs s\u00eb pacient\u00ebve.<\/p>\n<p>Si funksionon vaksina q\u00eb p\u00ebrshtatet p\u00ebr secilin pacient?<\/p>\n<p>Ndryshe nga vaksinat tradicionale, t\u00eb cilat zakonisht p\u00ebrdoren p\u00ebr parandalimin e s\u00ebmundjeve infektive, intismeran \u00ebsht\u00eb krijuar p\u00ebr trajtimin e pacient\u00ebve q\u00eb tashm\u00eb jan\u00eb diagnostikuar me melanom\u00eb.<\/p>\n<p>Ve\u00e7antia e saj q\u00ebndron te personalizimi. P\u00ebr secilin pacient analizohet nj\u00eb most\u00ebr e tumorit, p\u00ebr t\u00eb identifikuar ndryshimet gjenetike karakteristike t\u00eb qelizave kancerogjene.<\/p>\n<p>N\u00eb baz\u00eb t\u00eb k\u00ebtyre t\u00eb dh\u00ebnave krijohet nj\u00eb vaksin\u00eb e ve\u00e7ant\u00eb, e cila p\u00ebrdor teknologjin\u00eb mRNA p\u00ebr t\u2019i dh\u00ebn\u00eb sistemit imunitar udh\u00ebzime q\u00eb t\u00eb njoh\u00eb proteinat jonormale t\u00eb lidhura me tumorin.<\/p>\n<p>Q\u00ebllimi \u00ebsht\u00eb q\u00eb organizmi t\u00eb identifikoj\u00eb dhe t\u00eb sulmoj\u00eb qelizat kancerogjene q\u00eb mund t\u00eb ken\u00eb mbetur pas operacionit, duke zvog\u00ebluar mund\u00ebsin\u00eb e rikthimit t\u00eb s\u00ebmundjes.<\/p>\n<p>Vaksina jepet krahas imunoterapis\u00eb Keytruda, e cila ndihmon sistemin imunitar t\u00eb veproj\u00eb m\u00eb efektivisht kund\u00ebr kancerit.<\/p>\n<p>Nj\u00eb hap i r\u00ebnd\u00ebsish\u00ebm drejt trajtimit t\u00eb personalizuar t\u00eb kancerit<\/p>\n<p>St\u00e9phane Bancel, drejtor ekzekutiv i kompanis\u00eb Moderna, ka vler\u00ebsuar se rezultatet p\u00ebrforcojn\u00eb potencialin e teknologjis\u00eb mRNA p\u00ebr t\u00eb ndryshuar m\u00ebnyr\u00ebn e trajtimit t\u00eb kancerit.<\/p>\n<p>Nj\u00eb aspekt i r\u00ebnd\u00ebsish\u00ebm \u00ebsht\u00eb se vaksina nuk \u00ebsht\u00eb e nj\u00ebjt\u00eb p\u00ebr t\u00eb gjith\u00eb pacient\u00ebt, por krijohet sipas karakteristikave biologjike t\u00eb tumorit t\u00eb secilit individ.<\/p>\n<p>Kjo qasje p\u00ebrfaq\u00ebson nj\u00eb zhvillim t\u00eb r\u00ebnd\u00ebsish\u00ebm t\u00eb mjek\u00ebsis\u00eb s\u00eb personalizuar, ku trajtimi p\u00ebrshtatet sipas ve\u00e7orive molekulare t\u00eb s\u00ebmundjes.<\/p>\n<p>Megjithat\u00eb, rezultatet pozitive p\u00ebr melanom\u00ebn nuk n\u00ebnkuptojn\u00eb automatikisht se vaksinat e ngjashme do t\u00eb jen\u00eb po aq efektive kund\u00ebr llojeve t\u00eb tjera t\u00eb kancerit.<\/p>\n<p>Cilat jan\u00eb efektet an\u00ebsore dhe sa i sigurt \u00ebsht\u00eb trajtimi?<\/p>\n<p>Sipas t\u00eb dh\u00ebnave t\u00eb kompanive prodhuese, profili i siguris\u00eb ishte p\u00ebrgjith\u00ebsisht n\u00eb p\u00ebrputhje me studimet e m\u00ebparshme dhe nuk u identifikuan sinjale t\u00eb reja sigurie.<\/p>\n<p>Efektet m\u00eb t\u00eb shpeshta an\u00ebsore p\u00ebrfshinin temperatur\u00ebn, dhimbjen n\u00eb vendin e injektimit dhe lodhjen.<\/p>\n<p>Megjithat\u00eb, pacient\u00ebt duhet t\u00eb monitorohen nga specialist\u00ebt, pasi kombinimi me imunoterapin\u00eb mund t\u00eb shkaktoj\u00eb edhe reaksione m\u00eb serioze.<\/p>\n<p>Intismeran autogene ende nuk ka marr\u00eb miratimin e Administrat\u00ebs Amerikane t\u00eb Ushqimit dhe Barnave (FDA) p\u00ebr p\u00ebrdorim t\u00eb zakonsh\u00ebm klinik.<\/p>\n<p>Kompanit\u00eb Moderna dhe Merck kan\u00eb njoftuar se jan\u00eb n\u00eb komunikim me autoritetet rregullatore p\u00ebr hapat e ardhsh\u00ebm drejt miratimit.<\/p>\n<p>Procesi paraqet sfida t\u00eb ve\u00e7anta, pasi vaksina prodhohet individualisht p\u00ebr secilin pacient dhe k\u00ebrkon analiz\u00eb t\u00eb holl\u00ebsishme t\u00eb tumorit.<\/p>\n<p>Nd\u00ebrkoh\u00eb, studiuesit po shqyrtojn\u00eb p\u00ebrdorimin e vaksinave terapeutike t\u00eb bazuara n\u00eb teknologjin\u00eb mRNA edhe kund\u00ebr kancerit t\u00eb mushk\u00ebrive, pankreasit, veshkave dhe tumoreve t\u00eb tjera.<\/p>\n<p>Rezultatet e reja p\u00ebrfaq\u00ebsojn\u00eb nj\u00eb p\u00ebrparim inkurajues n\u00eb trajtimin e melanom\u00ebs, por vaksina mbetet eksperimentale. Studimet e m\u00ebtejshme dhe vler\u00ebsimi nga autoritetet sh\u00ebndet\u00ebsore do t\u00eb p\u00ebrcaktojn\u00eb n\u00ebse ajo mund t\u00eb b\u00ebhet pjes\u00eb e trajtimit standard p\u00ebr pacient\u00ebt me k\u00ebt\u00eb s\u00ebmundje.<\/p>\n<hr style=\"margin:30px 0\"\/>\n<p style=\"font-size:13px;color:#666\">Burimi: <strong>mesazhi<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vaksina e personalizuar, e zhvilluar nga Moderna dhe Merck, ka dh\u00ebn\u00eb rezultate premtuese n\u00eb faz\u00ebn e tret\u00eb t\u00eb studimeve klinike. Trajtimi ka ulur edhe rrezikun e p\u00ebrhapjes s\u00eb kancerit n\u00eb organe t\u00eb tjera, duke hapur mund\u00ebsi t\u00eb reja p\u00ebr pacient\u00ebt me melanom\u00eb Nj\u00eb vaksin\u00eb e re kund\u00ebr melanom\u00ebs, form\u00ebs m\u00eb vdekjeprur\u00ebse t\u00eb kancerit t\u00eb l\u00ebkur\u00ebs, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":119313,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-119314","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-shendetesi"],"_links":{"self":[{"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/posts\/119314","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/comments?post=119314"}],"version-history":[{"count":0,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/posts\/119314\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/media\/119313"}],"wp:attachment":[{"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/media?parent=119314"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/categories?post=119314"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/prizrenpost.com\/al\/wp-json\/wp\/v2\/tags?post=119314"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}