{"id":42105,"date":"2026-04-24T10:44:11","date_gmt":"2026-04-24T08:44:11","guid":{"rendered":"https:\/\/prizrenpost.com\/tr\/bu-eski-ilac-kanser-riskini-azaltabilir\/"},"modified":"2026-04-24T10:44:15","modified_gmt":"2026-04-24T08:44:15","slug":"bu-eski-ilac-kanser-riskini-azaltabilir","status":"publish","type":"post","link":"https:\/\/prizrenpost.com\/tr\/bu-eski-ilac-kanser-riskini-azaltabilir\/","title":{"rendered":"Bu eski ila\u00e7 kanser riskini azaltabilir"},"content":{"rendered":"

<\/p>\n

A\u011fr\u0131 ve ate\u015fi tedavi etmek i\u00e7in evrensel olarak basit bir ara\u00e7 olarak kabul edilen d\u00f6rt bin y\u0131ll\u0131k ila\u00e7 aspirin, modern onkolojideki en umut verici ke\u015fiflerden biri oldu\u011funu kan\u0131tl\u0131yor.<\/p>\n

Bu eski ila\u00e7, k\u00fcresel sa\u011fl\u0131k politikalar\u0131n\u0131 temelden de\u011fi\u015ftiren bulgular olan belirli t\u00fcm\u00f6r t\u00fcrlerinin olu\u015fumunu ve yay\u0131lmas\u0131n\u0131 \u00f6nleme konusunda dikkate de\u011fer bir yetenek g\u00f6stermi\u015ftir.<\/p>\n

Lynch Sendromu ta\u015f\u0131yan Nick James’in vakas\u0131, bu tedavinin g\u00fcc\u00fcn\u00fc g\u00f6stermektedir. On y\u0131l boyunca d\u00fczenli aspirin kullan\u0131m\u0131ndan sonra, y\u00fcksek genetik yatk\u0131nl\u0131\u011fa ra\u011fmen kanserden uzak kal\u0131yor.<\/p>\n

Lynch sendromu ba\u011f\u0131rsak kanseri riskini y\u00fczde 80’e kadar art\u0131r\u0131yor, ancak John Burn gibi profes\u00f6rler taraf\u0131ndan y\u00fcr\u00fct\u00fclen \u00e7al\u0131\u015fmalar, d\u00fc\u015f\u00fck g\u00fcnl\u00fck dozun bu riski yar\u0131 yar\u0131ya azaltabildi\u011fini kan\u0131tlad\u0131.<\/p>\n

Aspirinin tarihi, Mezopotamya’da kil tabletler ve bilmeden mideyi sakinle\u015ftirmek i\u00e7in salisin kullanan eski M\u0131s\u0131rl\u0131lar ve Yunanl\u0131lar taraf\u0131ndan s\u00f6\u011f\u00fct kabu\u011funun kullan\u0131lmas\u0131yla ba\u015flar. <\/p>\n

Bilim insanlar\u0131 asetilsalisilik asidi sentezlemeyi ancak 19. y\u00fczy\u0131lda ba\u015fard\u0131lar; bu asit mideyi daha az tahri\u015f eder ve s\u0131radan insanlar i\u00e7in daha eri\u015filebilir hale gelir.<\/p>\n

On y\u0131llar boyunca aspirin esas olarak kan suland\u0131r\u0131c\u0131 ve kardiyovask\u00fcler koruma i\u00e7in \u00f6nerildi, ancak 1972’den bu yana fareler \u00fczerinde yap\u0131lan ara\u015ft\u0131rmalar bunun metastaz\u0131 durdurabilece\u011fini \u00f6ne s\u00fcrd\u00fc.<\/p>\n

Bug\u00fcn bilim insanlarda giderek daha g\u00fc\u00e7l\u00fc kan\u0131tlar buluyor. \u0130sve\u00e7’te 2025’te yap\u0131lan son ara\u015ft\u0131rmalar, kolorektal kanseri atlatan ve ameliyattan sonra aspirin alan hastalar\u0131n hastal\u0131\u011f\u0131n tekrarlama ihtimalinin \u00e7ok daha d\u00fc\u015f\u00fck oldu\u011funu g\u00f6sterdi.<\/p>\n

Ancak bu s\u00fcrecin molek\u00fcler d\u00fczeyde nas\u0131l i\u015fledi\u011fi b\u00fcy\u00fck soru olarak kal\u0131yor. Aspirin, h\u00fccrenin hem i\u00e7inde hem de d\u0131\u015f\u0131nda \u00e7al\u0131\u015farak kontrols\u00fcz h\u00fccre b\u00fcy\u00fcmesi i\u00e7in sinyal yollar\u0131n\u0131 etkinle\u015ftiren Cox-2 enzimini inhibe eder.<\/p>\n

\u015ea\u015f\u0131rt\u0131c\u0131 yeni bir bulgu, aspirinin kanseri ba\u011f\u0131\u015f\u0131kl\u0131k sistemi taraf\u0131ndan “g\u00f6r\u00fcn\u00fcr” hale getirebildi\u011fini \u00f6ne s\u00fcr\u00fcyor. Aspirin, bir p\u0131ht\u0131la\u015fma fakt\u00f6r\u00fc olan tromboksan A2’yi bloke ederek kanser h\u00fccrelerinin koruyucu T h\u00fccreleri taraf\u0131ndan gizlenmesini \u00f6nler.<\/p>\n

Bu, ba\u011f\u0131\u015f\u0131kl\u0131k sistemimizin onlar\u0131 t\u00fcm\u00f6rler olu\u015fmadan \u00f6nce daha verimli bir \u015fekilde tan\u0131mlay\u0131p yok edebilece\u011fi anlam\u0131na gelir. Bu ke\u015fif, k\u00f6t\u00fc huylu h\u00fccrelerin kan yoluyla di\u011fer organlar\u0131 istila etti\u011fi metastaz s\u00fcrecini durdurmak i\u00e7in \u00f6zellikle \u00f6nemlidir.<\/p>\n

Ancak bu \u015fa\u015f\u0131rt\u0131c\u0131 sonu\u00e7lara ra\u011fmen doktorlar daha dikkatli olunmas\u0131 \u00e7a\u011fr\u0131s\u0131nda bulunuyor. Aspirin riskleri olmayan evrensel bir tedavi de\u011fildir. Doktora dan\u0131\u015fmadan i\u00e7ilirse i\u00e7 kanamaya, \u00fclsere ve kanamaya neden olabilir.<\/p>\n

Ayr\u0131ca elli ya\u015f\u0131n \u00fczerindeki herkesin \u00f6nleyici tedbir olarak almas\u0131 gerekip gerekmedi\u011fi konusunda tart\u0131\u015fmalar devam ediyor. Ancak \u00e7o\u011fu uzman, kullan\u0131m\u0131n\u0131n y\u00fcksek riskli gruplarla s\u0131n\u0131rl\u0131 olmas\u0131n\u0131 \u00f6nermektedir. \/tesheshi.com\/<\/p>\n

Tecr\u00fcbeyi geli\u015ftirmek ve reklamlar\u0131 g\u00f6r\u00fcnt\u00fclemek i\u00e7in \u00e7erezleri kullan\u0131yoruz (Google AdSense).
\n “Kabul Et” se\u00e7ene\u011fine t\u0131klayarak \u00e7erezlerin a\u015fa\u011f\u0131daki \u015fartlara g\u00f6re kullan\u0131lmas\u0131n\u0131 kabul etmi\u015f olursunuz.
\n Gizlilik Politikas\u0131
\n ve
\n \u00c7erez Politikas\u0131.
\n “Reddet”i t\u0131klayarak gerekli olmayan \u00e7erezleri reddedebilirsiniz.<\/p>\n

\n

Kaynak: prizrenpost<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

A\u011fr\u0131 ve ate\u015fi tedavi etmek i\u00e7in evrensel olarak basit bir ara\u00e7 olarak kabul edilen d\u00f6rt bin y\u0131ll\u0131k ila\u00e7 aspirin, modern onkolojideki en umut verici ke\u015fiflerden biri oldu\u011funu kan\u0131tl\u0131yor. Bu eski ila\u00e7, k\u00fcresel sa\u011fl\u0131k politikalar\u0131n\u0131 temelden de\u011fi\u015ftiren bulgular olan belirli t\u00fcm\u00f6r t\u00fcrlerinin olu\u015fumunu ve yay\u0131lmas\u0131n\u0131 \u00f6nleme konusunda dikkate de\u011fer bir yetenek g\u00f6stermi\u015ftir. Lynch Sendromu ta\u015f\u0131yan Nick […]<\/p>\n","protected":false},"author":1,"featured_media":42106,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-42105","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-teknoloji"],"views":5,"_links":{"self":[{"href":"https:\/\/prizrenpost.com\/tr\/wp-json\/wp\/v2\/posts\/42105","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/prizrenpost.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/prizrenpost.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/prizrenpost.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/prizrenpost.com\/tr\/wp-json\/wp\/v2\/comments?post=42105"}],"version-history":[{"count":1,"href":"https:\/\/prizrenpost.com\/tr\/wp-json\/wp\/v2\/posts\/42105\/revisions"}],"predecessor-version":[{"id":42107,"href":"https:\/\/prizrenpost.com\/tr\/wp-json\/wp\/v2\/posts\/42105\/revisions\/42107"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/prizrenpost.com\/tr\/wp-json\/wp\/v2\/media\/42106"}],"wp:attachment":[{"href":"https:\/\/prizrenpost.com\/tr\/wp-json\/wp\/v2\/media?parent=42105"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/prizrenpost.com\/tr\/wp-json\/wp\/v2\/categories?post=42105"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/prizrenpost.com\/tr\/wp-json\/wp\/v2\/tags?post=42105"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}